Chromatin conformation shapes the environment in which our genome is transcribed into RNA.Transcription is a source of DNA damage, thus it often occurs concomitantly to DNA damage signaling.Growing amounts of evidence suggest that different types of RNAs can, independently from their protein-coding properties, directly affect chromatin conformation
The ability to perform steady-state submaximal exercise at a certain intensity (exercise tolerance) predicts endurance performance in athletes, but also the quality of life and the capability to perform daily living activities in older people and patients suffering from chronic diseases.Improvements in exercise tolerance following exercise training
IntroductionFrom late 2014 through 2015, Scott County, Indiana faced an HIV outbreak triggered by opioid abuse and transition to injection drug use.Investigating the origins, risk factors, and responses related to this outbreak is critical to inform future surveillance, interventions, and policymaking.In response, this retrospective infoveillance s
Posterior reversible encephalopathy syndrome (PRES) is receiving increasing recognition in pediatrics.However, comparisons between PRES in cottonmouth 3.5 high shirt pediatric oncology and post-bone marrow transplantation (BMT) are lacking.Therefore, we aimed to describe the risk factors and clinical and radiological features of PRES and investigat